Keep Moving with Laxido Paediatric Plain
Macrogol 3350, sodium chloride, sodium hydrogen carbonate, potassium chloride
The information on this page is intended for UK Healthcare Professionals only.
This webpage is intended for UK healthcare professionals only
Constipation is common in childhood. It is prevalent in around 5% – 30% of the child population, depending on the criteria used for diagnosis.12
Laxido Paediatric Plain is indicated for the treatment of chronic constipation in children aged 1 to 11 years and is also effective in resolving faecal impaction, defined as refractory constipation with faecal loading of the rectum and/or colon, in children from the age of 5 years.³
6.9g powder sachet with the same active ingredients and pharmaceutical form as the originator macrogol 3350 plus electrolytes laxative brand for children3,16
Provides relief from chronic constipation in children from 1 years and above as well as faecal impaction in children aged 5 years and above3
Easy-to-mix macrogol 3350 plus electrolytes laxative formulation³
18% less expensive than the originator macrogol 3350 plus electrolytes laxative brand for children6
Each sachet of Laxido Paediatric Plain contains3:
Macrogol 3350 | 6.563g |
Sodium Chloride | 175.4mg |
Sodium Hydrogen Carbonate | 89.3mg |
Potassium Chloride | 25.1mg |
Macrogol 3350 induces a laxative effect by virtue of its osmotic action in the gut, which makes faeces softer and easier to pass. This product also contains electrolytes to ensure that there is no overall gain or loss of water, potassium or sodium.
Laxido Paediatric Plain dosage and treatment duration for children3
Condition | Dose | Duration |
---|---|---|
Chronic constipation children aged 1 to 11 years | Usual starting dose:
The dose should be adjusted up or down as required to produce regular soft stools. If the dose needs increasing this is best done every second day. For children below 2 years of age, the maximum recommended dose should not exceed 2 sachets a day. For children aged 2 to 11 years, the maximum recommended dose needed does not normally exceed 4 sachets a day. | Treatment of children with chronic constipation needs to be for a prolonged period (at least 6 to 12 months). However, safety and efficacy have only been proven for a period of up to 3 months. Treatment should be stopped gradually and resumed if constipation recurs. |
Faecal impaction children aged from 5 to 11 years. Not recommended for children under 5 years of age | A course of treatment is for up to 7 days as follows: Day 1 - 4 sachets, Day 2 - 6 sachets, Day 3 - 8 sachets, Day 4 - 10 sachets, Day 5 - 12 sachets, Day 6 - 12 sachets, Day 7 - 12 sachets. The daily number of sachets should be taken in divided doses, all consumed within a 12-hour period. | The dosage regimen should be stopped once disimpaction has occurred. |
Laxido Paediatric Plain is not recommended for children below 5 years of age for the treatment of faecal impaction, or in children below 1 year of age for the treatment of chronic constipation. For patients of 12 years and older it is recommended to use Laxido Orange.
Patients with impaired cardiovascular function: There are no clinical data for this group of patients. Therefore Laxido Paediatric Plain is not recommended for treating faecal impaction in children with impaired cardiovascular function.
Patients with renal insufficiency: There are no clinical data for this group of patients. Therefore Laxido Paediatric Plain is not recommended for treating faecal impaction in children with impaired renal function.
Each sachet should be dissolved in 62.5 ml (quarter of a glass) of water, to make a clear or slightly hazy solution. The correct number of sachets may be reconstituted in advance and kept covered and refrigerated for up to 24 hours. For example, for use in faecal impaction, 12 sachets can be made up into 750 ml of water.
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Contact UsAdverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Galen Limited on 028 3833 4974 and select the customer services option, or e-mail customer.services@galen-pharma.com. Medical information enquiries should also be directed to Galen Limited.
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